More Dead Ends and Detours. En Route to Successful Total Synthesis

Success comes in many forms and in synthesis it can be a failure that results in their ultimate successful solutions. This long-awaited sequel to «Dead Ends and Detours» retains the proven concept while featuring over 20 new case studies of failed strategies and their (successful) solutions in natural product total synthesis. Additionally, computational models are used to discuss the problem in much more detail and to provide readers with additional information not found in the primary literature. The topics range from classic synthetic reactions (e.g. Diels Alder reaction), metal-mediated coupling reactions, metathesis, and asymmetric catalysis to the importance of prote…